Alexander Golovanov
Senior Lecturer at Alliance Manchester Business School
Schools
- Alliance Manchester Business School
Links
Biography
Alliance Manchester Business School
Overview
Probably all life processes are controlled by proteins. Proteins interact with each other and these interactions form giant networks which researchers only recently started to unravel. The primary research in my group is devoted to understanding of how proteins interact with themselves and with each other, and how their interactions are linked to diseases, such as viral infection, inflammation and cancer. If we understand the critical interactions causing the problems, we can change these interactions using carefully designed therapeutic drugs. One of the methods which we use is Nuclear Magnetic Resonance (NMR) spectroscopy, which allows us to look inside molecules, determining their shape and form, and mapping protein interaction interfaces. By observing the signals from each atom, the minute details of protein interactions can be revealed. Apart from looking at “useful” protein interactions, we are also interested in finding ways to prevent proteins from clumping together non-specifically, forming aggregates. We look at novel ways to prevent protein aggregation which would enable faster development of new protein-based biopharmaceuticals (such as antibodies) able to treat wide range of diseases, from autoimmune disorders to cancer. This may make injections of such new drugs less painful as well!
Biography
Alexander Golovanov is a Senior Lecturer in the School of Chemistry, Faculty of Science and Engineering, working in the field of structural biology. His lab is located in the Manchester Institute of Biotechnology (MIB).
Alexander graduated in 1988 from the Moscow Institute of Physics and Technology (Russia) with the degree equivalent to MSc. He then joined NMR group in Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry (Russian Academy of Sciences) and worked there with Professor Arseniev for a number of years. Alexander obtained his PhD in 1994 doing the project in the same group, and then became the member of staff, subsequently being promoted all the way from Junior to Senior Investigator.
In 1998 Alexander came to Leicester University (UK) to work as a Research Associate with Professor Gordon Roberts and Professor Lu-Yun Lian. In 2000 Alexander has moved to Manchester to be appointed as an Experimental Officer and NMR Manager in the University of Manchester Institute of Science and Technology. He was promoted to Senior Experimental Officer shortly after, in 2001. From 2006 Alexander moved to academic position in the Faculty of Life Sciences, The University of Manchester.
Read about executive education
Other experts
Fabio Scacciavillani
Mr. Scacciavillani is the Chief Economist of the Oman Investment Fund and a member of its Investment Committee. In this role, he develops forecasts, conducts analyses of global economic trends, and contributes to decisions on asset management strategy. Previously he served as Director of Macroeco...
David P. Newton
Research interests I am currently particularly interested in 1) development of new techniques for valuing derivatives, an area where my research group members and I already have papers published and 2) development and empirical testing of structural bond default models, a related area involving t...
Margaret Rudolf
Margaret recently completed a 30-year career in senior management with the federal government of Canada. Her work experience ranges from advising Cabinet Ministers on communications change issues, to managing complex transformational projects in a number of large organizations. A native of Montre...
Popular Courses
The Positive Leader: Deep Change and Organizational Transformation
Stephen M. Ross School of Business
Ann Arbor, Michigan, United States
Jun 23
Private Equity: Investing and Creating Value
The Wharton School
Philadelphia, Pennsylvania, United States
Sep 8
Leading People and Teams
ESMT
Berlin, Germany
May 28
Leading Strategic Growth and Change
Columbia Business School
New York, New York, United States
Jun 10
The Manchester Leadership Development Programme
Alliance Manchester Business School
Manchester, United Kingdom
Jul 1
Leading Digital Transformation
ESMT
Berlin, Germany
May 28
Looking for an expert?
Contact us and we'll find the best option for you.