Darrell Kotton

Dr. Kotton is Assistant Professor in the Department of Pathology and Laboratory Medicine as well as in the Department of Medicine. He attends in the Medical Intensive Care Unit and on the Pulmonary Consultation Service at Boston Medical Center.

Dr. Kotton’s research focuses on stem cell biology and gene therapy related to lung injury and repair. He is an NIH-funded Principal Investigator and a member of several research groups, including the Stem Cell Biology and Gene Therapy Group, and the Pulmonary Developmental Biology Group. Dr. Kotton’s laboratory currently utilizes several stem cell populations, including bone marrow-derived stem cells and embryonic stem cells in order to develop novel stem cell-based therapies for lung disease. In addition, Dr. Kotton specializes in the genetic manipulation of stem cells as well as resident lung cells using lentiviral vectors. Projects in his lab are currently focused on utilizing these novel vectors for the study of alpha-1 anti-trypsin deficiency, COPD, and lung inflammatory pathways.