Liang Yang

Yang Liang, professor of the School of Medicine Southern University of Science and Technology. Dr. Yang obtained his Bachelor’s degree in Biological Sciences from Nankai University in 2004, and Ph.D., from Technical University of Denmark in 2009. Dr. Yang joined the School of Biological Sciences, Nanyang Technological University, Singapore as Assistant Professor from 2012, and obtained tenure (Associate Professor) in 2018. Dr. Yang was nominated as Assistant Dean of the School of Biological Sciences, and Deputy Research Director of Public Health & Medical Biofilms in Singapore Centre for Environmental Life Sciences Engineering (SCELSE). Dr. Yang joined the School of Medicine, Southern University of Science and Technology as a full-time professor at the end of 2018. He was granted the Guangdong Outstanding Youth Fund, the Oversea High-Caliber Personnel (Level B) of Shenzhen.

Dr. Yang is currently in charge of 3 core teaching courses: "Medical Microbiology (Undergraduate)", "Medical Microbiology Experiment (Undergraduate)" and "Microbial Technology (Graduate)" at Southern University of Science and Technology.

Research Interests

• Microbiology, infection, epidemiology, resistance gene transmission, biofilm, quorum sensing, drug development

Teaching

• Lecturer: Medical Microbiology (Undergraduate)
• Speaker: Medical Microbiology Experiment (Undergraduate)
• Speaker: Microbial Technology (Graduate)

Educational Background

• 2000-2004 B.S., Nankai University
• 2004-2006 M.S., Danish Technical University
• 2006-2009 Ph.D., Technical University of Denmark

Professional experience

• 2009-2010 Postdoctoral, Danish Technical University
• 2011-2012 Postdoctoral, University of Hamburg (Germany)
• 2012 / 02-2012 / 06 Postdoctoral, Nanyang Technological University (Singapore)
• 2012 / 07-2018 / 02 Nanyang Technological University (Singapore) Assistant Professor
• 2018 / 03-2018 / 09 Nanyang Technological University (Singapore) Associate Professor
• 2018 / 10-present Professor of Southern University of Science and Technology

Honors & Awards

• 2007 American Microbiological Society Student Conference Travel Award
• 2010 Danish Medical Research Council Independent Postdoctoral Fund
• 2011 Humboldt Foundation Postdoctoral Scholarship, Germany
• 2011 FEMS Conference Young Scientist Travel Award
• 2012 Nanyang Assistant Professor Award, Singapore
• 2018 Tenure at Nanyang Technological University, Singapore
• 2019 Shenzhen Peacock Talent Class B
• 2019 Young Yangtze River Scholars
• 2020 Guangdong Outstanding Youth Fund

Professional Activities

2007-present: Member of American Society of Microbiology 2017-present: Member of International Society for Chemical Biology 2018-present: Editorial member of Biofilm (ISSN: 2590-2075). 2017- 2019: Editorial board member of Applied and Environmental Microbiology (Print ISSN: 0099-2240; Online ISSN: 1098-5336) 2015- 2016: Editorial Board of "New Horizons in Translational Medicine" (Official Journal of the European Society of Translational Medicine)

Microbiology, Environmental Microbiology, Environmental Microbiology Reports, Antimicrobial Agents and Chemotherapy, Medicinal Research Reviews, Applied and Environmental Microbiology, Journal of Antimicrobial Chemotherapy, Applied Microbiology and Biotechnology, PNAS, ISME J, Scientific Reports, BMC Microbiology, PLoS Pathogens, PLoS one, Reviewers in Trends in Biotechnology, Molecular Systems Biology, Current Opinion in Microbiology, Journal of Biochemistry, Chemical Communications, Water Research, ACS Chemical Biology, etc.

Selected Publication

Dispersed cells represent a distinct stage in the transition from bacterial biofilm to planktonic lifestyles. NATURE COMMUNICATIONS 2014

In vitro and in vivo generation and characterization of Pseudomonas aeruginosa biofilm–dispersed cells via c-di-GMP manipulation. Nature Protocols 2015

Selective labelling and eradication of antibiotictolerant bacterial populations in Pseudomonas aeruginosa biofilms. NATURE COMMUNICATIONS 2016

A cyclic di-GMP-binding adaptor protein interacts with a chemotaxis methyltransferase to control flagellar motor switching. SCIENCE SIGNALING 2016

Ribosome protection by antibiotic resistance ATP-binding cassette protein. PNAS 2018

Journal Papers

The research team has trained more than 10 Ph.D. students and more than 10 Postdoctoral students. International academic journals include Lancet, Nature Communications, Science Signaling, Nature Protocols, Proc Natl Acad. Sci USA, Trends in Microbiology, mBio, Nano Letters, Current Opinion in Biotechnology, Briefings in Bioinformatics, Journal of Medicinal Chemistry, etc. Published more than 140 papers. The paper has been cited more than 8,000 times, H-Index 43 (Google Scholar). Professor Yang Liang has been invited to make academic reports more than 30 times in international academic conferences, universities and researches in the United States, Canada, Germany, Japan, Singapore and other countries.

Invention patent

Quorum Sensing Inhibitors. Sean Yang-Yi Tan, Liang Yang, Michael Givskov. US patent granted (US9988380B2)

Method Of Inhibiting Quorum Sensing In Pseudomonas Aeruginosa. Michael Christian Givskov, Shu Sin Chng, Liang Yang, Zhen Wei Leon Tan, Ziyan Hong. International patent filed (PCT/SG2016/050436)

Chemical Fluorescent Probes For Detecting Biofilms. Young-Tae Chang, Jun-Young Kim, Sahu SRIKANTA, Michael Christian Givskov, Liang Yang. International patent filed (US10416153B2)

Authored Books

Yang Liang, Wu Hong (2012). Microbial interactions and signal transmission in biofilms. "Microbial Biofilm and Infection", People's Medical Publishing House, ISBN-9787117156462

Yang Liang, Song Zhijun (2012). Multiple Species Bacterial Biofilms and Infection. "Microbial Biofilm and Infection", People's Medical Publishing House, ISBN-9787117156462

Chew SC, Yang L(2015) Biofilms. Encyclopedia of Food and Health. Elsevier, ISBN-9780123849533

den BestenH, Ding Y, Abee T, Yang L (2015) Emergent Strategies for Detection and Control of Biofilms in Food Processing Environments. Advances in Food Biotechnology. John Wiley & Sons, ISBN-9781118864555

Yang L, Chua SL (2017) Proteogenomics of Pseudomonas aeruginosain cystic fibrosis infections. MALDI-TOF and Tandem MS for Clinical Microbiology, John Wiley & Sons, ISBN: 9781118960257

Duang X, Fu Y, Yang L (2020). Molecular and Systems biology approaches for analyzing drug-tolerant bacterial persister cells. Mitigation of Antimicrobial Resistance, Springer Nature