Susan Bookheimer

Dr. Susan Bookheimer is the Joaquin M. Fuster Chair in Cognitive Neuroscience at the David Geffen School of Medicine at UCLA. She is a clinical neuropsychologist with a broad interest in the study of human cognition in relation to brain structure, function, and pathology, and her experimental expertise includes structural and functional MRI (fMRI), positron emission tomography, and intraoperative electrocortical stimulation mapping, as well as classical neuropsychological approaches. She has special interests in epilepsy, autism, and Alzheimer’s disease. Her recent work focuses on understanding the neural basis of social communication deficits in autism using fMRI, encompassing both verbal and nonverbal communication, and focusing on emotional aspects of social comprehension. Dr. Bookheimer serves as the principal investigator of the UCLA Autism Center of Excellence grant, with UCLA being one of the only centers for three consecutive grant cycles due to its scientific excellence. She also serves as the principal investigator at the UCLA Intellectual and Developmental Disabilities Research Center. She has published more than 215 articles in the field of neurological and neurodevelopmental disabilities and has been a leader in the field of autism neuroimaging.

Education

• Ph.D. Wayne State University (1982 — 1985)
• BA Cornell University (1980 — 1982)
• Bachelor's degree Cornell University

Interests

• Functional Brain Imaging
• Autism
• Alzheimer's
• Brain Tumors
• Epilepsy

Publications

A selected list of publications:

• Ecker Christine, Bookheimer Susan Y, Murphy Declan G M Neuroimaging in autism spectrum disorder: brain structure and function across the lifespan The Lancet. Neurology, 2015; 14(11): 1121-34.
• Tomson Steffie N, Schreiner Matthew J, Narayan Manjari, Rosser Tena, Enrique Nicole, Silva Alcino J, Allen Genevera I, Bookheimer Susan Y, Bearden Carrie E Resting state functional MRI reveals abnormal network connectivity in neurofibromatosis 1 Human brain mapping, 2015; 36(11): 4566-81.
• Harrison Theresa M, Burggren Alison C, Small Gary W, Bookheimer Susan Y Altered memory-related functional connectivity of the anterior and posterior hippocampus in older adults at increased genetic risk for Alzheimer's disease Human brain mapping, 2015; 14(11): .
• Thames April D, Sayegh Philip, Terashima Kevin, Foley Jessica M, Cho Andrew, Arentoft Alyssa, Hinkin Charles H, Bookheimer Susan Y Increased subcortical neural activity among HIV+ individuals during a lexical retrieval task Neurobiology of disease, 2015; 14(11): .
• Feusner Jamie D, Dervisic Jasenko, Kosidou Kyriaki, Dhejne Cecilia, Bookheimer Susan, Savic Ivanka Female-to-Male Transsexual Individuals Demonstrate Different Own Body Identification Archives of sexual behavior, 2015; 14(11): .
• Green Shulamite A, Hernandez Leanna, Tottenham Nim, Krasileva Kate, Bookheimer Susan Y, Dapretto Mirella Neurobiology of Sensory Overresponsivity in Youth With Autism Spectrum Disorders JAMA psychiatry, 2015; 72(8): 778-86.
• Suthana Nanthia A, Parikshak Neelroop N, Ekstrom Arne D, Ison Matias J, Knowlton Barbara J, Bookheimer Susan Y, Fried Itzhak Specific responses of human hippocampal neurons are associated with better memory Proceedings of the National Academy of Sciences of the United States of America, 2015; 112(33): 10503-8.
• Suthana Nanthia A, Donix Markus, Wozny David R, Bazih Adam, Jones Michael, Heidemann Robin M, Trampel Robert, Ekstrom Arne D, Scharf Maria, Knowlton Barbara, Turner Robert, Bookheimer Susan Y High-resolution 7T fMRI of Human Hippocampal Subfields during Associative Learning Journal of cognitive neuroscience, 2015; 27(6): 1194-206.
• Penfold Conor, Vizueta Nathalie, Townsend Jennifer D, Bookheimer Susan Y, Altshuler Lori L Frontal lobe hypoactivation in medication-free adults with bipolar II depression during response inhibition Psychiatry research, 2015; 231(3): 202-9.
• Wagshal Dana, Knowlton Barbara Jean, Cohen Jessica Rachel, Bookheimer Susan Yost, Bilder Robert Martin, Fernandez Vindia Gisela, Asarnow Robert Franklin Cognitive correlates of gray matter abnormalities in adolescent siblings of patients with childhood-onset schizophrenia Schizophrenia research, 2015; 161(2-3): 345-50.
• Połczyńska Monika M, Benjamin Christopher F A, Moseley Brian D, Walshaw Patricia, Eliashiv Dawn, Vigil Celia, Jones Michael, Bookheimer Susan Y Role of the Wada test and functional magnetic resonance imaging in preoperative mapping of language and memory: two atypical cases Neurocase, 2015; 21(6): 707-20.
• Hernandez Leanna M, Rudie Jeffrey D, Green Shulamite A, Bookheimer Susan, Dapretto Mirella Neural signatures of autism spectrum disorders: insights into brain network dynamics Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015; 40(1): 171-89.
• Połczyńska Monika, Curtiss Susan, Walshaw Particia, Siddarth Prabha, Benjamin Chris, Moseley Brian D, Vigil Celia, Jones Michael, Eliashiv Dawn, Bookheimer Susan Grammar tests increase the ability to lateralize language function in the Wada test Epilepsy research, 2014; 108(10): 1864-73.
• Wagshal Dana, Knowlton Barbara Jean, Suthana Nanthia Ananda, Cohen Jessica Rachel, Poldrack Russel Alan, Bookheimer Susan Yost, Bilder Robert Martin, Asarnow Robert Franklin Evidence for corticostriatal dysfunction during cognitive skill learning in adolescent siblings of patients with childhood-onset schizophrenia Schizophrenia bulletin, 2014; 40(5): 1030-9.
• Loring David W, Gaillard William Davis, Bookheimer Susan Y, Meador Kimford J, Ojemann Jeffrey G Cortical cartography reveals political and physical maps Epilepsia, 2014; 55(5): 633-7.
• Zheng Zhong, Shemmassian Shirag, Wijekoon Christopher, Kim Won, Bookheimer Susan Y, Pouratian Nader DTI correlates of distinct cognitive impairments in Parkinson's disease Human brain mapping, 2014; 35(4): 1325-33.
• Chen Stephen T, Siddarth Prabha, Saito Nathan Y, Rueda Flori, Haight Taylor, Ercoli Linda M, Miller Karen J, Lavretsky Helen, Barrio Jorge R, Bookheimer Susan Y, Small Gary W, Merrill David A Psychological well-being and regional brain amyloid and tau in mild cognitive impairment The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2014; 22(4): 362-9.
• Wagshal Dana, Knowlton Barbara Jean, Cohen Jessica Rachel, Poldrack Russell Alan, Bookheimer Susan Yost, Bilder Robert Martin, Asarnow Robert Franklin Impaired automatization of a cognitive skill in first-degree relatives of patients with schizophrenia Psychiatry research, 2014; 215(2): 294-9.
• Harris Robert J, Bookheimer Susan Y, Cloughesy Timothy F, Kim Hyun J, Pope Whitney B, Lai Albert, Nghiemphu Phioanh L, Liau Linda M, Ellingson Benjamin M Altered functional connectivity of the default mode network in diffuse gliomas measured with pseudo-resting state fMRI Journal of neuro-oncology, 2014; 116(2): 373-9.
• Donix Markus, Burggren Alison C, Scharf Maria, Marschner Kira, Suthana Nanthia A, Siddarth Prabha, Krupa Allison K, Jones Michael, Martin-Harris Laurel, Ercoli Linda M, Miller Karen J, Werner Annett, von Kummer Rüdiger, Sauer Cathrin, Small Gary W, Holthoff Vjera A, Bookheimer Susan Y APOE associated hemispheric asymmetry of entorhinal cortical thickness in aging and Alzheimer's disease Psychiatry research, 2013; 214(3): 212-20.
• Braskie Meredith N, Medina Luis D, Rodriguez-Agudelo Yaneth, Geschwind Daniel H, Macias-Islas Miguel Angel, Thompson Paul M, Cummings Jeffrey L, Bookheimer Susan Y, Ringman John M Memory performance and fMRI signal in presymptomatic familial Alzheimer's disease Human brain mapping, 2013; 34(12): 3308-19.
• Torrisi Salvatore J, Lieberman Matthew D, Bookheimer Susan Y, Altshuler Lori L Advancing understanding of affect labeling with dynamic causal modeling NeuroImage, 2013; 82(12): 481-8.
• Green Shulamite A, Rudie Jeffrey D, Colich Natalie L, Wood Jeffrey J, Shirinyan David, Hernandez Leanna, Tottenham Nim, Dapretto Mirella, Bookheimer Susan Y Overreactive brain responses to sensory stimuli in youth with autism spectrum disorders Journal of the American Academy of Child and Adolescent Psychiatry, 2013; 52(11): 1158-72.
• Gee Dylan G, Gabard-Durnam Laurel J, Flannery Jessica, Goff Bonnie, Humphreys Kathryn L, Telzer Eva H, Hare Todd A, Bookheimer Susan Y, Tottenham Nim Early developmental emergence of human amygdala-prefrontal connectivity after maternal deprivation Proceedings of the National Academy of Sciences of the United States of America, 2013; 110(39): 15638-43.
• Townsend Jennifer D, Sugar Catherine A, Walshaw Patricia D, Vasquez Roxanne E, Foland-Ross Lara C, Moody Teena D, Bookheimer Susan Y, McGough James J, Altshuler Lori L Frontostriatal neuroimaging findings differ in patients with bipolar disorder who have or do not have ADHD comorbidity Journal of affective disorders, 2013; 147(1-3): 389-96.
• Gee Dylan G, Humphreys Kathryn L, Flannery Jessica, Goff Bonnie, Telzer Eva H, Shapiro Mor, Hare Todd A, Bookheimer Susan Y, Tottenham Nim A developmental shift from positive to negative connectivity in human amygdala-prefrontal circuitry The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013; 33(10): 4584-93.
• Torrisi Salvatore, Moody Teena D, Vizueta Nathalie, Thomason Moriah E, Monti Martin M, Townsend Jennifer D, Bookheimer Susan Y, Altshuler Lori L Differences in resting corticolimbic functional connectivity in bipolar I euthymia Bipolar disorders, 2013; 15(2): 156-66.
• Small Gary W, Kepe Vladimir, Siddarth Prabha, Ercoli Linda M, Merrill David A, Donoghue Natacha, Bookheimer Susan Y, Martinez Jacqueline, Omalu Bennet, Bailes Julian, Barrio Jorge R PET scanning of brain tau in retired national football league players: preliminary findings The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2013; 21(2): 138-44.