Caroline Sands

She is a postdoctoral research chemometrician at the MRC-NIHR Phenome Centre, a world-class facility for the metabolic phenotyping of human samples. She contributes to quality-control assessment, method development and biomarker discovery and validation in patient- and population-based samples with the overarching aim of discovering robust diagnostic and prognostic markers for disease risk and personalized medicine.

As such, her main research interests include:

• elucidating the complex relationship between health status, diet, genetics, drugs, microbiome and environment in metabolic phenotyping based analysis of patients and populations
• development of statistical methods for enhanced information recovery from spectroscopic data.

Education

• Imperial College London - Master’s Degree, MSc Bioinformatics and Systems Biology 2006 - 2007
• Imperial College London - BSc, Biochemistry with a Year in Research 2001 - 2005

Selected Publications

Sands CJ; Coen M; Ebbels TMD; Holmes E; Lindon JC; Nicholson JK. (2011). Data-Driven Approach for Metabolite Relationship Recovery in Biological 1H NMR Data Sets Using Iterative Statistical Total Correlation Spectroscopy. Analytical Chemistry. 83:2075-2082.

Sands CJ; Coen M; Maher AD; Ebbels TMD; Holmes E; Lindon JC; Nicholson JK. (2009). Statistical Total Correlation Spectroscopy Editing of 1H NMR Spectra of Biofluids: Application to Drug Metabolite Profile Identification and Enhanced Information Recovery. Analytical Chemistry. 81:6458-6466.